Combine Ingredients: In the medium saucepan, combine the 2 cups Peaches, 1 cups Bourbon, 1 cups Ketchup, 1/2 cups Apple cider vinegar, and 1/2 cups Brown sugar.
Simmer: Bring the mixture to a simmer over medium heat, stirring occasionally.
Season: Add 1/4 cups Worcestershire sauce, 1 tbsp Smoked paprika, 1 tsp Garlic powder, 1 tsp Onion powder, 1/2 tsp Salt, and 1/4 tsp Black pepper to the saucepan.
Blend: After simmering for 20 minutes, use a blender or immersion blender to blend the sauce until smooth.
Boil: Return the blended sauce to a boil, then reduce heat and simmer for an additional 10 minutes.
Cool and Store: Allow the sauce to cool before transferring it to a jar or container for storage.